An efficient stereoselective synthesis of cytotoxic 8-epipuupehedione.
نویسندگان
چکیده
An efficient and highly stereoselective synthesis of cytotoxic 8-epipuupehedione (1b) was achieved starting from natural (-)-drimenol (6). The key step to obtain stereoselectivity was the simultaneous demethylation and oxidation of the dihydrobenzopyran methoxy derivatives 10a and 10b.
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عنوان ژورنال:
- Journal of natural products
دوره 66 10 شماره
صفحات -
تاریخ انتشار 2003